Within the dermis, a dense community of ECM proteins offers structural assist to the pores and skin and regulates a large variety of signaling pathways which govern cell proliferation and different crucial processes. Both intrinsic ageing, which happens steadily over time, and extrinsic ageing (photoaging), which happens as a consequence of exterior insults such as photo voltaic radiation, trigger alterations to the dermal ECM. In this examine, we utilized each quantitative and world proteomics, alongside single harmonic era (SHG) and two-photon autofluorescence (TPAF) imaging, to assess modifications in dermal composition throughout intrinsic and extrinsic ageing.
We discover that each intrinsic and extrinsic ageing consequence in important decreases in ECM-supporting proteoglycans and structural ECM integrity, evidenced by reducing collagen abundance and rising fibril fragmentation. Intrinsic ageing additionally produces modifications distinct from these produced by photoaging, including reductions in elastic fiber and crosslinking enzyme abundance. In distinction, photoaging is primarily outlined by will increase in elastic fiber-associated protein and pro-inflammatory proteases. Network evaluation steered that AM and Bk have been accountable for PHN preliminary assault, whereas Inq, B, T and Bc-h would degrade PHN metabolites.
Changes related with photoaging are evident even in younger (mid 20s) sun-exposed forearm pores and skin, indicating that proteomic proof of photoaging is current many years prior to clinical indicators of photoaging. GO time period enrichment revealed that each intrinsic ageing and photoaging share widespread options of persistent irritation. The proteomic data has been deposited to the ProteomeXchange Consortium by way of the PRIDE associate repository with the data set identifier PXD015982.
Quantitative proteomic profiling of extracellular matrix and site-specific collagen post-translational modifications in an in vitro mannequin of lung fibrosis
Lung fibrosis is characterised by extreme deposition of extracellular matrix (ECM), in particular collagens, by fibroblasts in the interstitium. Transforming development factor-β1 (TGF-β1) alters the expression of many extracellular matrix (ECM) elements produced by fibroblasts, however such modifications in ECM composition as effectively as modulation of collagen post-translational modification (PTM) levels have not been comprehensively investigated. Here, we carried out mass spectrometry (MS)-based proteomics analyses to assess modifications in the ECM deposited by cultured lung fibroblasts from idiopathic pulmonary fibrosis (IPF) sufferers upon stimulation with remodeling development issue β1 (TGF-β1).
In addition to the ECM modifications generally related with lung fibrosis, MS-based label-free quantification revealed profound results on enzymes concerned in ECM crosslinking and turnover as effectively as a number of constructive and unfavorable suggestions mechanisms of TGF-β1 signaling. Notably, the ECM modifications noticed in this in vitro mannequin correlated considerably with ECM modifications noticed in affected person samples. Because collagens are topic to a number of PTMs with main implications in illness, we carried out a new bioinformatic platform to analyze MS data that enables for the complete mapping and site-specific quantitation of collagen PTMs in crude ECM preparations.
These analyses yielded a complete map of prolyl and lysyl hydroxylations as effectively as lysyl glycosylations for 15 collagen chains. In addition, site-specific PTM evaluation revealed novel websites of prolyl-3-hydroxylation and lysyl glycosylation in sort I collagen. Interestingly, the outcomes present, for the first time, that TGF-β1 can modulate prolyl-3-hydroxylation and glycosylation in a site-specific method. Taken collectively, this proof of idea examine not solely reveals unanticipated TGF-β1 mediated regulation of collagen PTMs and different ECM elements but additionally lays the basis for dissecting their key roles in well being and illness.

Time-resolved Analysis of the Matrix Metalloproteinase 10 Substrate Degradome
Proteolysis is an irreversible post-translational modification that impacts intra- and intercellular communication by modulating the exercise of bioactive mediators. Key to understanding protease operate is the system-wide identification of cleavage occasions and their dynamics in physiological contexts. Despite recent advances in mass spectrometry-based proteomics for high-throughput substrate screening, present approaches endure from excessive false constructive charges and solely seize single states of protease exercise. Here, we current a workflow primarily based on multiplexed terminal amine isotopic labeling of substrates for time-resolved substrate degradomics in complicated proteomes.
This method considerably enhances confidence in substrate identification and categorizes cleavage occasions by specificity and structural accessibility of the cleavage web site. We reveal concomitant quantification of cleavage web site spanning peptides and neo-N and/or neo-C termini to estimate relative ratios of noncleaved and cleaved varieties of substrate proteins. By making use of this technique to dissect the matrix metalloproteinase 10 (MMP10) substrate degradome in fibroblast secretomes, we recognized the extracellular matrix protein ADAMTS-like protein 1 (ADAMTSL1) as a direct MMP10 substrate and revealed MMP10-dependent ectodomain shedding of platelet-derived development issue receptor alpha (PDGFRα) as effectively as sequential processing of sort I collagen.
anti- Podoplanin antibody |
FNab06598 |
FN Test |
100µg |
EUR 585 |
|
Description: Antibody raised against Podoplanin |
anti- Podoplanin antibody |
FNab06599 |
FN Test |
100µg |
EUR 585 |
|
Description: Antibody raised against Podoplanin |
Rabbit Polyclonal antibody Anti-CRBN |
Anti-CRBN |
ImmunoStep |
50 µg |
EUR 349 |
Anti-Podoplanin/gp36/PDPN Antibody |
A01124 |
BosterBio |
100ug/vial |
EUR 294 |
Anti-D2-40/Podoplanin antibody |
STJ190048 |
St John's Laboratory |
200 µl |
EUR 197 |
Description: Unconjugated Mouse monoclonal to D2-40/Podoplanin (7D1) |
Anti-Podoplanin Rabbit Monoclonal Antibody |
M01124-1 |
BosterBio |
100ug/vial |
EUR 397 |
Description: Rabbit Monoclonal Podoplanin Antibody. Validated in WB and tested in Human, Mouse, Rat. |
Anti-Podoplanin Rabbit Monoclonal Antibody |
M01124-2 |
BosterBio |
100ug/vial |
EUR 397 |
Description: Rabbit Monoclonal Podoplanin Antibody. Validated in WB and tested in Human. |
Anti-Podoplanin/gp36/PDPN Antibody |
PA1411 |
BosterBio |
100ug/vial |
EUR 294 |
Anti-Podoplanin/gp36/PDPN Antibody |
PA1674 |
BosterBio |
100ug/vial |
EUR 294 |
Anti-Podoplanin/gp36/PDPN Antibody |
PA1675 |
BosterBio |
100ug/vial |
EUR 294 |
Mouse Podoplanin ELISA kit |
E03P0082-192T |
BlueGene |
192 tests |
EUR 1270 |
|
Description: A sandwich ELISA for quantitative measurement of Mouse Podoplanin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Podoplanin ELISA kit |
E03P0082-48 |
BlueGene |
1 plate of 48 wells |
EUR 520 |
|
Description: A sandwich ELISA for quantitative measurement of Mouse Podoplanin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Podoplanin ELISA kit |
E03P0082-96 |
BlueGene |
1 plate of 96 wells |
EUR 685 |
|
Description: A sandwich ELISA for quantitative measurement of Mouse Podoplanin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Mouse Podoplanin (PDPN) Protein |
20-abx650139 |
Abbexa |
-
EUR 648.00
-
EUR 272.00
-
EUR 1943.00
-
EUR 759.00
-
EUR 467.00
|
-
100 ug
-
10 ug
-
1 mg
-
200 ug
-
50 ug
|
|
Polyclonal Goat anti-GST α-form |
GST-ANTI-1 |
Detroit R&D |
50 uL |
EUR 280 |
Polyclonal Goat anti-GST μ-form |
GST-ANTI-2 |
Detroit R&D |
50 uL |
EUR 280 |
Polyclonal Goat anti-GST p-form |
GST-ANTI-3 |
Detroit R&D |
50 uL |
EUR 280 |
Podoplanin antibody |
70R-PR007 |
Fitzgerald |
100 ug |
EUR 422 |
Description: Affinity purified Rabbit polyclonal Podoplanin antibody |
Podoplanin antibody |
70R-50819 |
Fitzgerald |
100 ul |
EUR 244 |
Description: Purified Polyclonal Podoplanin antibody |
Podoplanin antibody |
70R-6816 |
Fitzgerald |
50 ug |
EUR 467 |
Description: Rabbit polyclonal Podoplanin antibody raised against the N terminal of PDPN |
Podoplanin antibody |
70R-6817 |
Fitzgerald |
50 ug |
EUR 467 |
Description: Rabbit polyclonal Podoplanin antibody raised against the middle region of PDPN |
Podoplanin antibody |
70R-11540 |
Fitzgerald |
100 ug |
EUR 527 |
Description: Rabbit polyclonal Podoplanin antibody |
Podoplanin antibody |
70R-13952 |
Fitzgerald |
100 ug |
EUR 305 |
Description: Affinity purified Rabbit polyclonal Podoplanin antibody |
Podoplanin antibody |
10R-P133a |
Fitzgerald |
100 ug |
EUR 507 |
Description: Mouse monoclonal Podoplanin antibody |
Podoplanin antibody |
10R-P155a |
Fitzgerald |
100 ug |
EUR 543 |
Description: Hamster monoclonal Podoplanin antibody |
Podoplanin antibody |
10R-7662 |
Fitzgerald |
100 ug |
EUR 629 |
Description: Mouse monoclonal Podoplanin antibody |
Podoplanin antibody |
10R-7663 |
Fitzgerald |
100 ug |
EUR 629 |
Description: Hamster monoclonal Podoplanin antibody |
Podoplanin antibody |
10R-7664 |
Fitzgerald |
100 ug |
EUR 629 |
Description: Mouse monoclonal Podoplanin antibody |
Podoplanin Antibody |
DF12456 |
Affbiotech |
200ul |
EUR 304 |
Description: Podoplanin antibody detects endogenous levels of Podoplanin. |
Podoplanin Antibody |
49474-100ul |
SAB |
100ul |
EUR 333 |
Podoplanin Antibody |
49474-50ul |
SAB |
50ul |
EUR 239 |
Podoplanin Antibody |
P1051-01m |
SAB |
0.1m |
EUR 209 |
Podoplanin Antibody |
P1051-1ml |
SAB |
1ml |
EUR 941 |
Mouse Anti-Human Podoplanin monoclonal antibody, clone JID761 |
CABT-L2919-100uL500uL |
Creative Diagnostics |
100 uL, 500 uL |
EUR 502 |
Recombinant Mouse Podoplanin (C-Fc) |
CU73-10ug |
Novoprotein |
10ug |
EUR 131 |
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
Recombinant Mouse Podoplanin (C-Fc) |
CU73-1mg |
Novoprotein |
1mg |
EUR 1674 |
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
Recombinant Mouse Podoplanin (C-Fc) |
CU73-500ug |
Novoprotein |
500ug |
EUR 1166 |
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
Recombinant Mouse Podoplanin (C-Fc) |
CU73-50ug |
Novoprotein |
50ug |
EUR 273 |
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
Podoplanin (PDPN) Polyclonal Antibody (Mouse) |
4-PAC719Mu01 |
Cloud-Clone |
-
EUR 251.00
-
EUR 2576.00
-
EUR 640.00
-
EUR 316.00
-
EUR 215.00
|
-
100ul
-
10ml
-
1ml
-
200ul
-
20ul
|
|
Description: A Rabbit polyclonal antibody against Mouse Podoplanin (PDPN) |
Mouse Podoplanin (PDPN) ELISA Kit |
SEC719Mu-10x96wellstestplate |
Cloud-Clone |
10x96-wells test plate |
EUR 4862.4 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Podoplanin (PDPN) in tissue homogenates, cell lysates and other biological fluids. |
Mouse Podoplanin (PDPN) ELISA Kit |
SEC719Mu-1x48wellstestplate |
Cloud-Clone |
1x48-wells test plate |
EUR 488.08 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Podoplanin (PDPN) in tissue homogenates, cell lysates and other biological fluids. |
Mouse Podoplanin (PDPN) ELISA Kit |
SEC719Mu-1x96wellstestplate |
Cloud-Clone |
1x96-wells test plate |
EUR 654.4 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Podoplanin (PDPN) in tissue homogenates, cell lysates and other biological fluids. |
Mouse Podoplanin (PDPN) ELISA Kit |
SEC719Mu-5x96wellstestplate |
Cloud-Clone |
5x96-wells test plate |
EUR 2644.8 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Podoplanin (PDPN) in tissue homogenates, cell lysates and other biological fluids. |
Mouse Podoplanin (PDPN) ELISA Kit |
4-SEC719Mu |
Cloud-Clone |
-
EUR 4913.00
-
EUR 2595.00
-
EUR 655.00
|
-
10 plates of 96 wells
-
5 plates of 96 wells
-
1 plate of 96 wells
|
|
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Podoplanin (PDPN) in samples from tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species. |
Mouse Podoplanin (PDPN) ELISA Kit |
abx571749-96tests |
Abbexa |
96 tests |
EUR 786 |
|
Mouse Podoplanin (PDPN) CLIA Kit |
20-abx493858 |
Abbexa |
-
EUR 7973.00
-
EUR 4246.00
-
EUR 981.00
|
-
10 × 96 tests
-
5 × 96 tests
-
96 tests
|
|
Mouse Podoplanin (PDPN) ELISA Kit |
20-abx154564 |
Abbexa |
-
EUR 7378.00
-
EUR 3933.00
-
EUR 911.00
|
-
10 × 96 tests
-
5 × 96 tests
-
96 tests
|
|
Mouse Podoplanin (PDPN) ELISA Kit |
DLR-PDPN-Mu-48T |
DL Develop |
48T |
EUR 527 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Podoplanin (PDPN) in samples from tissue homogenates, cell lysates or other biological fluids. |
Mouse Podoplanin (PDPN) ELISA Kit |
DLR-PDPN-Mu-96T |
DL Develop |
96T |
EUR 688 |
|
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Podoplanin (PDPN) in samples from tissue homogenates, cell lysates or other biological fluids. |
Mouse Podoplanin (PDPN) ELISA Kit |
RD-PDPN-Mu-48Tests |
Reddot Biotech |
48 Tests |
EUR 533 |
Mouse Podoplanin (PDPN) ELISA Kit |
RD-PDPN-Mu-96Tests |
Reddot Biotech |
96 Tests |
EUR 740 |
Mouse Podoplanin (PDPN) ELISA Kit |
RDR-PDPN-Mu-48Tests |
Reddot Biotech |
48 Tests |
EUR 557 |
Mouse Podoplanin (PDPN) ELISA Kit |
RDR-PDPN-Mu-96Tests |
Reddot Biotech |
96 Tests |
EUR 774 |
Podoplanin Blocking Peptide |
33R-2420 |
Fitzgerald |
100 ug |
EUR 180 |
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of PDPN antibody, catalog no. 70R-6816 |
Podoplanin Blocking Peptide |
33R-9441 |
Fitzgerald |
100 ug |
EUR 180 |
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of PDPN antibody, catalog no. 70R-6817 |
Podoplanin Blocking Peptide |
DF12456-BP |
Affbiotech |
1mg |
EUR 195 |
Recombinant Podoplanin (PDPN) |
4-RPC719Hu01 |
Cloud-Clone |
-
EUR 413.60
-
EUR 214.00
-
EUR 1276.00
-
EUR 492.00
-
EUR 884.00
-
EUR 340.00
-
EUR 3040.00
|
-
100 ug
-
10ug
-
1 mg
-
200 ug
-
500 ug
-
50ug
-
5 mg
|
|
Description: Recombinant Human Podoplanin expressed in: E.coli |
Recombinant Podoplanin (PDPN) |
4-RPC719Mu01 |
Cloud-Clone |
-
EUR 458.40
-
EUR 226.00
-
EUR 1444.00
-
EUR 548.00
-
EUR 996.00
-
EUR 370.00
-
EUR 3460.00
|
-
100 ug
-
10ug
-
1 mg
-
200 ug
-
500 ug
-
50ug
-
5 mg
|
|
Description: Recombinant Mouse Podoplanin expressed in: E.coli |
Podoplanin (PDPN) Antibody |
20-abx129101 |
Abbexa |
-
EUR 425.00
-
EUR 133.00
-
EUR 1205.00
-
EUR 578.00
-
EUR 328.00
|
-
100 ug
-
10 ug
-
1 mg
-
200 ug
-
50 ug
|
|
Podoplanin (PDPN) Antibody |
20-abx131102 |
Abbexa |
-
EUR 439.00
-
EUR 133.00
-
EUR 1233.00
-
EUR 592.00
-
EUR 328.00
|
-
100 ug
-
10 ug
-
1 mg
-
200 ug
-
50 ug
|
|
Podoplanin (PDPN) Antibody |
20-abx114559 |
Abbexa |
|
|
|
Podoplanin (PDPN) Antibody |
20-abx123399 |
Abbexa |
-
EUR 592.00
-
EUR 857.00
-
EUR 411.00
|
|
|
Podoplanin (PDPN) Antibody |
20-abx339428 |
Abbexa |
|
|
|
Podoplanin (PDPN) Antibody |
abx433110-200ul |
Abbexa |
200 ul |
EUR 384 |
|
Podoplanin (PDPN) Protein |
20-abx262003 |
Abbexa |
-
EUR 4490.00
-
EUR 328.00
-
EUR 230.00
|
|
|
Podoplanin (PDPN) Antibody |
abx236598-100ug |
Abbexa |
100 ug |
EUR 551 |
|
Podoplanin (PDPN) Antibody |
abx236599-100ug |
Abbexa |
100 ug |
EUR 551 |
|
Podoplanin (PDPN) Antibody |
20-abx211099 |
Abbexa |
|
|
|
Podoplanin (PDPN) Antibody |
20-abx178065 |
Abbexa |
|
|
|
Podoplanin (PDPN) Antibody |
20-abx178066 |
Abbexa |
|
|
|
Podoplanin (PDPN) Antibody |
20-abx178067 |
Abbexa |
|
|
|
Podoplanin (PDPN) Antibody |
20-abx174125 |
Abbexa |
|
|
|
Podoplanin (PDPN) Antibody |
20-abx174126 |
Abbexa |
|
|
|
Podoplanin Blocking Peptide |
20-abx063694 |
Abbexa |
|
|
|
Recombinant Human Podoplanin |
7-05840 |
CHI Scientific |
25µg |
Ask for price |
Podoplanin (PDPN) Antibody |
20-abx137407 |
Abbexa |
-
EUR 704.00
-
EUR 328.00
-
EUR 230.00
|
|
|
Podoplanin (PDPN) Antibody |
20-abx005408 |
Abbexa |
-
EUR 411.00
-
EUR 592.00
-
EUR 182.00
-
EUR 314.00
|
-
100 ul
-
200 ul
-
20 ul
-
50 ul
|
|
Podoplanin (PDPN) Antibody |
20-abx008317 |
Abbexa |
-
EUR 300.00
-
EUR 439.00
-
EUR 189.00
|
|
|
Podoplanin Conjugated Antibody |
C49474 |
SAB |
100ul |
EUR 397 |
Podoplanin (PDPN) Polyclonal Antibody (Mouse), APC |
4-PAC719Mu01-APC |
Cloud-Clone |
-
EUR 351.00
-
EUR 3365.00
-
EUR 935.00
-
EUR 449.00
-
EUR 222.00
|
-
100ul
-
10ml
-
1ml
-
200ul
-
20ul
|
|
Description: A Rabbit polyclonal antibody against Mouse Podoplanin (PDPN). This antibody is labeled with APC. |
Podoplanin (PDPN) Polyclonal Antibody (Mouse), Biotinylated |
4-PAC719Mu01-Biotin |
Cloud-Clone |
-
EUR 316.00
-
EUR 2526.00
-
EUR 744.00
-
EUR 387.00
-
EUR 221.00
|
-
100ul
-
10ml
-
1ml
-
200ul
-
20ul
|
|
Description: A Rabbit polyclonal antibody against Mouse Podoplanin (PDPN). This antibody is labeled with Biotin. |
Podoplanin (PDPN) Polyclonal Antibody (Mouse), Cy3 |
4-PAC719Mu01-Cy3 |
Cloud-Clone |
-
EUR 427.00
-
EUR 4445.00
-
EUR 1205.00
-
EUR 557.00
-
EUR 254.00
|
-
100ul
-
10ml
-
1ml
-
200ul
-
20ul
|
|
Description: A Rabbit polyclonal antibody against Mouse Podoplanin (PDPN). This antibody is labeled with Cy3. |
Podoplanin (PDPN) Polyclonal Antibody (Mouse), FITC |
4-PAC719Mu01-FITC |
Cloud-Clone |
-
EUR 301.00
-
EUR 2712.00
-
EUR 768.00
-
EUR 379.00
-
EUR 197.00
|
-
100ul
-
10ml
-
1ml
-
200ul
-
20ul
|
|
Description: A Rabbit polyclonal antibody against Mouse Podoplanin (PDPN). This antibody is labeled with FITC. |
Podoplanin (PDPN) Polyclonal Antibody (Mouse), HRP |
4-PAC719Mu01-HRP |
Cloud-Clone |
-
EUR 321.00
-
EUR 2933.00
-
EUR 827.00
-
EUR 405.00
-
EUR 209.00
|
-
100ul
-
10ml
-
1ml
-
200ul
-
20ul
|
|
Description: A Rabbit polyclonal antibody against Mouse Podoplanin (PDPN). This antibody is labeled with HRP. |
Podoplanin (PDPN) Polyclonal Antibody (Mouse), PE |
4-PAC719Mu01-PE |
Cloud-Clone |
-
EUR 301.00
-
EUR 2712.00
-
EUR 768.00
-
EUR 379.00
-
EUR 197.00
|
-
100ul
-
10ml
-
1ml
-
200ul
-
20ul
|
|
Description: A Rabbit polyclonal antibody against Mouse Podoplanin (PDPN). This antibody is labeled with PE. |
ELISA kit for Mouse PDPN (Podoplanin) |
E-EL-M2409 |
Elabscience Biotech |
1 plate of 96 wells |
EUR 534 |
|
Description: A sandwich ELISA kit for quantitative measurement of Mouse PDPN (Podoplanin) in samples from Serum, Plasma, Cell supernatant |
ELISA kit for Mouse Podoplanin (PDPN) |
KTE70775-48T |
Abbkine |
48T |
EUR 332 |
|
Description: Quantitative sandwich ELISA for measuring Mouse Podoplanin (PDPN) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Mouse Podoplanin (PDPN) |
KTE70775-5platesof96wells |
Abbkine |
5 plates of 96 wells |
EUR 2115 |
|
Description: Quantitative sandwich ELISA for measuring Mouse Podoplanin (PDPN) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Mouse Podoplanin (PDPN) |
KTE70775-96T |
Abbkine |
96T |
EUR 539 |
|
Description: Quantitative sandwich ELISA for measuring Mouse Podoplanin (PDPN) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Mouse PDPN (Podoplanin) |
ELK7080 |
ELK Biotech |
1 plate of 96 wells |
EUR 432 |
|
Description: A sandwich ELISA kit for detection of Podoplanin from Mouse in samples from blood, serum, plasma, cell culture fluid and other biological fluids. |
Syrian Hamster Anti-Mouse Podoplanin (gp38) Monoclonal antibody, clone 8.1.1 |
CABT-L4294-1mg |
Creative Diagnostics |
1 mg |
EUR 897 |
Syrian Hamster Anti-Mouse Podoplanin (gp38) Monoclonal antibody, clone 8.1.1 |
CABT-L4294-5mg |
Creative Diagnostics |
5 mg |
EUR 2405 |
Anti-Podoplanin Antibody Clone PDPN/1433, Unconjugated-100ug |
10630-MSM1-P1 |
EnQuireBio |
100ug |
EUR 428 |
Human Podoplanin ELISA kit |
E01P0082-192T |
BlueGene |
192 tests |
EUR 1270 |
|
Description: A sandwich ELISA for quantitative measurement of Human Podoplanin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Podoplanin ELISA kit |
E01P0082-48 |
BlueGene |
1 plate of 48 wells |
EUR 520 |
|
Description: A sandwich ELISA for quantitative measurement of Human Podoplanin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Podoplanin ELISA kit |
E01P0082-96 |
BlueGene |
1 plate of 96 wells |
EUR 685 |
|
Description: A sandwich ELISA for quantitative measurement of Human Podoplanin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Podoplanin ELISA kit |
E02P0082-192T |
BlueGene |
192 tests |
EUR 1270 |
|
Description: A sandwich ELISA for quantitative measurement of Rat Podoplanin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Podoplanin ELISA kit |
E02P0082-48 |
BlueGene |
1 plate of 48 wells |
EUR 520 |
|
Description: A sandwich ELISA for quantitative measurement of Rat Podoplanin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Podoplanin ELISA kit |
E02P0082-96 |
BlueGene |
1 plate of 96 wells |
EUR 685 |
|
Description: A sandwich ELISA for quantitative measurement of Rat Podoplanin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog Podoplanin ELISA kit |
E08P0082-192T |
BlueGene |
192 tests |
EUR 1270 |
|
Description: A sandwich ELISA for quantitative measurement of Canine Podoplanin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog Podoplanin ELISA kit |
E08P0082-48 |
BlueGene |
1 plate of 48 wells |
EUR 520 |
|
Description: A sandwich ELISA for quantitative measurement of Canine Podoplanin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Dog Podoplanin ELISA kit |
E08P0082-96 |
BlueGene |
1 plate of 96 wells |
EUR 685 |
|
Description: A sandwich ELISA for quantitative measurement of Canine Podoplanin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Goat Podoplanin ELISA kit |
E06P0082-192T |
BlueGene |
192 tests |
EUR 1270 |
|
Description: A sandwich ELISA for quantitative measurement of Goat Podoplanin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Goat Podoplanin ELISA kit |
E06P0082-48 |
BlueGene |
1 plate of 48 wells |
EUR 520 |
|
Description: A sandwich ELISA for quantitative measurement of Goat Podoplanin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Goat Podoplanin ELISA kit |
E06P0082-96 |
BlueGene |
1 plate of 96 wells |
EUR 685 |
|
Description: A sandwich ELISA for quantitative measurement of Goat Podoplanin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig Podoplanin ELISA kit |
E07P0082-192T |
BlueGene |
192 tests |
EUR 1270 |
|
Description: A sandwich ELISA for quantitative measurement of Porcine Podoplanin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig Podoplanin ELISA kit |
E07P0082-48 |
BlueGene |
1 plate of 48 wells |
EUR 520 |
|
Description: A sandwich ELISA for quantitative measurement of Porcine Podoplanin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Pig Podoplanin ELISA kit |
E07P0082-96 |
BlueGene |
1 plate of 96 wells |
EUR 685 |
|
Description: A sandwich ELISA for quantitative measurement of Porcine Podoplanin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rabbit Podoplanin ELISA kit |
E04P0082-192T |
BlueGene |
192 tests |
EUR 1270 |
|
Description: A sandwich ELISA for quantitative measurement of Rabbit Podoplanin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rabbit Podoplanin ELISA kit |
E04P0082-48 |
BlueGene |
1 plate of 48 wells |
EUR 520 |
|
Description: A sandwich ELISA for quantitative measurement of Rabbit Podoplanin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rabbit Podoplanin ELISA kit |
E04P0082-96 |
BlueGene |
1 plate of 96 wells |
EUR 685 |
|
Description: A sandwich ELISA for quantitative measurement of Rabbit Podoplanin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Monkey Podoplanin ELISA kit |
E09P0082-192T |
BlueGene |
192 tests |
EUR 1270 |
|
Description: A sandwich ELISA for quantitative measurement of Monkey Podoplanin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Monkey Podoplanin ELISA kit |
E09P0082-48 |
BlueGene |
1 plate of 48 wells |
EUR 520 |
|
Description: A sandwich ELISA for quantitative measurement of Monkey Podoplanin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Monkey Podoplanin ELISA kit |
E09P0082-96 |
BlueGene |
1 plate of 96 wells |
EUR 685 |
|
Description: A sandwich ELISA for quantitative measurement of Monkey Podoplanin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Rat Podoplanin (PDPN) Protein |
20-abx654779 |
Abbexa |
-
EUR 578.00
-
EUR 258.00
-
EUR 1720.00
-
EUR 690.00
-
EUR 425.00
|
-
100 ug
-
10 ug
-
1 mg
-
200 ug
-
50 ug
|
|
Cow Podoplanin (PDPN) Protein |
20-abx654780 |
Abbexa |
-
EUR 648.00
-
EUR 272.00
-
EUR 1998.00
-
EUR 773.00
-
EUR 467.00
|
-
100 ug
-
10 ug
-
1 mg
-
200 ug
-
50 ug
|
|
Human Podoplanin (PDPN) Protein |
20-abx166428 |
Abbexa |
-
EUR 578.00
-
EUR 258.00
-
EUR 1720.00
-
EUR 690.00
-
EUR 425.00
|
-
100 ug
-
10 ug
-
1 mg
-
200 ug
-
50 ug
|
|
Podoplanin (PDPN) Antibody (Cy3) |
20-abx274445 |
Abbexa |
-
EUR 551.00
-
EUR 272.00
-
EUR 1720.00
-
EUR 787.00
-
EUR 439.00
|
-
100 ug
-
10 ug
-
1 mg
-
200 ug
-
50 ug
|
|
Podoplanin (PDPN) Polyclonal Antibody (Mouse), APC-Cy7 |
4-PAC719Mu01-APC-Cy7 |
Cloud-Clone |
-
EUR 583.00
-
EUR 6610.00
-
EUR 1750.00
-
EUR 778.00
-
EUR 324.00
|
-
100ul
-
10ml
-
1ml
-
200ul
-
20ul
|
|
Description: A Rabbit polyclonal antibody against Mouse Podoplanin (PDPN). This antibody is labeled with APC-Cy7. |
Human Podoplanin (PDPN) ELISA Kit |
SEC719Hu-10x96wellstestplate |
Cloud-Clone |
10x96-wells test plate |
EUR 4731.5 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Podoplanin (PDPN) in Tissue homogenates, cell lysates and other biological fluids. |
Human Podoplanin (PDPN) ELISA Kit |
SEC719Hu-1x48wellstestplate |
Cloud-Clone |
1x48-wells test plate |
EUR 477.3 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Podoplanin (PDPN) in Tissue homogenates, cell lysates and other biological fluids. |
Human Podoplanin (PDPN) ELISA Kit |
SEC719Hu-1x96wellstestplate |
Cloud-Clone |
1x96-wells test plate |
EUR 639 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Podoplanin (PDPN) in Tissue homogenates, cell lysates and other biological fluids. |
Human Podoplanin (PDPN) ELISA Kit |
SEC719Hu-5x96wellstestplate |
Cloud-Clone |
5x96-wells test plate |
EUR 2575.5 |
|
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Podoplanin (PDPN) in Tissue homogenates, cell lysates and other biological fluids. |
Two artificial bacterial consortia (SC) composed of bacterial strains Sphingobium sp. (AM), Klebsiella aerogenes (B), Pseudomonas sp. (Bc-h and T), Burkholderia sp. (Bk) and Inquilinus limosus (Inq) remoted from a pure phenanthrene (PHN)-degrading consortium (CON) have been developed and evaluated as an various method to PHN biodegradation in bioremediation processes. A metabolic community displaying the potential function of strains was reconstructed by in silico examine of the six genomes and classification of dioxygenase enzymes utilizing RHObase and AromaDeg databases. The predicted roles have been additional confirmed by physiological, RT-qPCR and metaproteomic assays. SC-1 with AM as the sole PHN degrader was the most efficient. The ecological roles inferred in this examine might be utilized to optimize the design of bacterial consortia and sort out the biodegradation of complicated environmental pollution.