Human pores and skin is composed of the cell-rich dermis, the extracellular matrix (ECM) wealthy dermis, and the hypodermis.

Within the dermis, a dense community of ECM proteins offers structural assist to the pores and skin and regulates a large variety of signaling pathways which govern cell proliferation and different crucial processes. Both intrinsic ageing, which happens steadily over time, and extrinsic ageing (photoaging), which happens as a consequence of exterior insults such as photo voltaic radiation, trigger alterations to the dermal ECM. In this examine, we utilized each quantitative and world proteomics, alongside single harmonic era (SHG) and two-photon autofluorescence (TPAF) imaging, to assess modifications in dermal composition throughout intrinsic and extrinsic ageing.

We discover that each intrinsic and extrinsic ageing consequence in important decreases in ECM-supporting proteoglycans and structural ECM integrity, evidenced by reducing collagen abundance and rising fibril fragmentation. Intrinsic ageing additionally produces modifications distinct from these produced by photoaging, including reductions in elastic fiber and crosslinking enzyme abundance. In distinction, photoaging is primarily outlined by will increase in elastic fiber-associated protein and pro-inflammatory proteases. Network evaluation steered that AM and Bk have been accountable for PHN preliminary assault, whereas Inq, B, T and Bc-h would degrade PHN metabolites.

Changes related with photoaging are evident even in younger (mid 20s) sun-exposed forearm pores and skin, indicating that proteomic proof of photoaging is current many years prior to clinical indicators of photoaging. GO time period enrichment revealed that each intrinsic ageing and photoaging share widespread options of persistent irritation. The proteomic data has been deposited to the ProteomeXchange Consortium by way of the PRIDE associate repository with the data set identifier PXD015982.

Quantitative proteomic profiling of extracellular matrix and site-specific collagen post-translational modifications in an in vitro mannequin of lung fibrosis

Lung fibrosis is characterised by extreme deposition of extracellular matrix (ECM), in particular collagens, by fibroblasts in the interstitium. Transforming development factor-β1 (TGF-β1) alters the expression of many extracellular matrix (ECM) elements produced by fibroblasts, however such modifications in ECM composition as effectively as modulation of collagen post-translational modification (PTM) levels have not been comprehensively investigated. Here, we carried out mass spectrometry (MS)-based proteomics analyses to assess modifications in the ECM deposited by cultured lung fibroblasts from idiopathic pulmonary fibrosis (IPF) sufferers upon stimulation with remodeling development issue β1 (TGF-β1).

In addition to the ECM modifications generally related with lung fibrosis, MS-based label-free quantification revealed profound results on enzymes concerned in ECM crosslinking and turnover as effectively as a number of constructive and unfavorable suggestions mechanisms of TGF-β1 signaling. Notably, the ECM modifications noticed in this in vitro mannequin correlated considerably with ECM modifications noticed in affected person samples. Because collagens are topic to a number of PTMs with main implications in illness, we carried out a new bioinformatic platform to analyze MS data that enables for the complete mapping and site-specific quantitation of collagen PTMs in crude ECM preparations.

These analyses yielded a complete map of prolyl and lysyl hydroxylations as effectively as lysyl glycosylations for 15 collagen chains. In addition, site-specific PTM evaluation revealed novel websites of prolyl-3-hydroxylation and lysyl glycosylation in sort I collagen. Interestingly, the outcomes present, for the first time, that TGF-β1 can modulate prolyl-3-hydroxylation and glycosylation in a site-specific method. Taken collectively, this proof of idea examine not solely reveals unanticipated TGF-β1 mediated regulation of collagen PTMs and different ECM elements but additionally lays the basis for dissecting their key roles in well being and illness.

The identification of specific protein kinases as oncogenic drivers in a variety of cancer sorts, coupled with the clinical success of particular kinase-directed targeted therapies, has cemented the human kinome as an attractive source of 'actionable' targets for cancer remedy. However, 'mining' of the human kinome for precision oncology applications has yet to yield its full potential. This reflects a variety of points, including oncogenic kinase dysregulation at levels not detectable by genomic sequencing and the uncharacterized nature of a considerable fraction of the kinome. In addition, selective therapeutic targeting of specific kinases requires efficient mapping of total kinome space impacted by candidate small molecule medication. Fortunately, recent developments in proteomics strategies, particularly in mass spectrometry-based phosphoproteomics and kinomics, provide the necessary technology platforms to address these impediments. Moreover, initiatives such as the Clinical Proteomic Tumour Analysis Consortium have enabled the era, deposition and integration of genomic, transcriptomic and (phospho)proteomic data for many cancer sorts, providing unprecedented insights into oncogenic kinases and cancer cell signalling typically. These multi-omic data are identifying novel therapeutic targets, highlighting opportunities for drug re-purposing, and helping assign optimal therapies to specific tumour subtypes, heralding a new era of 'enhanced' precision oncology. This article is protected by copyright. All rights reserved.

Time-resolved Analysis of the Matrix Metalloproteinase 10 Substrate Degradome

Proteolysis is an irreversible post-translational modification that impacts intra- and intercellular communication by modulating the exercise of bioactive mediators. Key to understanding protease operate is the system-wide identification of cleavage occasions and their dynamics in physiological contexts. Despite recent advances in mass spectrometry-based proteomics for high-throughput substrate screening, present approaches endure from excessive false constructive charges and solely seize single states of protease exercise. Here, we current a workflow primarily based on multiplexed terminal amine isotopic labeling of substrates for time-resolved substrate degradomics in complicated proteomes.

This method considerably enhances confidence in substrate identification and categorizes cleavage occasions by specificity and structural accessibility of the cleavage web site. We reveal concomitant quantification of cleavage web site spanning peptides and neo-N and/or neo-C termini to estimate relative ratios of noncleaved and cleaved varieties of substrate proteins. By making use of this technique to dissect the matrix metalloproteinase 10 (MMP10) substrate degradome in fibroblast secretomes, we recognized the extracellular matrix protein ADAMTS-like protein 1 (ADAMTSL1) as a direct MMP10 substrate and revealed MMP10-dependent ectodomain shedding of platelet-derived development issue receptor alpha (PDGFRα) as effectively as sequential processing of sort I collagen.

anti- Podoplanin antibody
FNab06598 100µg
EUR 585
  • Recommended dilution: WB: 1:500-1:2000
  • IHC: 1:20-1:200
  • Immunogen: podoplanin
  • Uniprot ID: Q86YL7
  • Research Area: Metabolism, Cardiovascular, Immunology, Cancer, Developmental biology, Stem Cells
Description: Antibody raised against Podoplanin

anti- Podoplanin antibody
FNab06599 100µg
EUR 585
  • Recommended dilution: WB: 1:500 - 1:2000
  • Immunogen: PDPN
  • Uniprot ID: Q86YL7
  • Research Area: Metabolism, Cardiovascular, Immunology, Cancer, Developmental biology, Stem Cells
Description: Antibody raised against Podoplanin

Anti-Podoplanin antibody
PAab06598 100 ug
EUR 412

Anti-Podoplanin antibody
PAab06599 100 ug
EUR 412

Anti-Podoplanin antibody
STJ180226 0.1 ml
EUR 266

Anti-Podoplanin antibody
STJ180283 0.1 ml
EUR 223

Rabbit Polyclonal antibody Anti-CRBN
Anti-CRBN 50 µg
EUR 349

Podoplanin
MO47016 100 ul
EUR 349

Anti-Podoplanin/gp36/PDPN Antibody
A01124 100ug/vial
EUR 294

Anti-Podoplanin/gp36/PDPN Antibody
PA1411 100ug/vial
EUR 294

Anti-Podoplanin/gp36/PDPN Antibody
PA1674 100ug/vial
EUR 294

Anti-Podoplanin/gp36/PDPN Antibody
PA1675 100ug/vial
EUR 294

Anti-Podoplanin Rabbit Monoclonal Antibody
M01124-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal Podoplanin Antibody. Validated in WB and tested in Human, Mouse, Rat.

Anti-Podoplanin Rabbit Monoclonal Antibody
M01124-2 100ug/vial
EUR 397
Description: Rabbit Monoclonal Podoplanin Antibody. Validated in WB and tested in Human.

Anti-D2-40 Podoplanin antibody
STJ16100360 1 mL
EUR 1235

Anti-D2-40/Podoplanin antibody
STJ190048 200 µl
EUR 197
Description: Unconjugated Mouse monoclonal to D2-40/Podoplanin (7D1)

Mouse Podoplanin ELISA kit
E03P0082-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A sandwich ELISA for quantitative measurement of Mouse Podoplanin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Podoplanin ELISA kit
E03P0082-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A sandwich ELISA for quantitative measurement of Mouse Podoplanin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Podoplanin ELISA kit
E03P0082-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A sandwich ELISA for quantitative measurement of Mouse Podoplanin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Podoplanin (PDPN) Protein
20-abx650139
  • EUR 648.00
  • EUR 272.00
  • EUR 1943.00
  • EUR 759.00
  • EUR 467.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Mouse Anti-Human Podoplanin monoclonal antibody, clone JID761
CABT-L2919-100uL500uL 100 uL, 500 uL
EUR 502

Podoplanin antibody
70R-11540 100 ug
EUR 527
Description: Rabbit polyclonal Podoplanin antibody

Podoplanin antibody
70R-13952 100 ug
EUR 305
Description: Affinity purified Rabbit polyclonal Podoplanin antibody

Podoplanin antibody
10R-P133a 100 ug
EUR 507
Description: Mouse monoclonal Podoplanin antibody

Podoplanin antibody
10R-P155a 100 ug
EUR 543
Description: Hamster monoclonal Podoplanin antibody

Podoplanin antibody
10R-7662 100 ug
EUR 629
Description: Mouse monoclonal Podoplanin antibody

Podoplanin antibody
10R-7663 100 ug
EUR 629
Description: Hamster monoclonal Podoplanin antibody

Podoplanin antibody
10R-7664 100 ug
EUR 629
Description: Mouse monoclonal Podoplanin antibody

Podoplanin Antibody
49474-100ul 100ul
EUR 333

Podoplanin Antibody
49474-50ul 50ul
EUR 239

Podoplanin Antibody
DF12456 200ul
EUR 304
Description: Podoplanin antibody detects endogenous levels of Podoplanin.

Podoplanin antibody
70R-PR007 100 ug
EUR 422
Description: Affinity purified Rabbit polyclonal Podoplanin antibody

Podoplanin antibody
70R-50819 100 ul
EUR 244
Description: Purified Polyclonal Podoplanin antibody

Podoplanin antibody
70R-6816 50 ug
EUR 467
Description: Rabbit polyclonal Podoplanin antibody raised against the N terminal of PDPN

Podoplanin antibody
70R-6817 50 ug
EUR 467
Description: Rabbit polyclonal Podoplanin antibody raised against the middle region of PDPN

Podoplanin Antibody
P1051-01m 0.1m
EUR 209

Podoplanin Antibody
P1051-1ml 1ml
EUR 941

Polyclonal Goat anti-GST α-form
GST-ANTI-1 50 uL
EUR 280

Polyclonal Goat anti-GST μ-form
GST-ANTI-2 50 uL
EUR 280

Polyclonal Goat anti-GST p-form
GST-ANTI-3 50 uL
EUR 280

Mouse Podoplanin (PDPN) ELISA Kit
DLR-PDPN-Mu-48T 48T
EUR 527
  • Should the Mouse Podoplanin (PDPN) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Podoplanin (PDPN) in samples from tissue homogenates, cell lysates or other biological fluids.

Mouse Podoplanin (PDPN) ELISA Kit
DLR-PDPN-Mu-96T 96T
EUR 688
  • Should the Mouse Podoplanin (PDPN) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Podoplanin (PDPN) in samples from tissue homogenates, cell lysates or other biological fluids.

Recombinant Mouse Podoplanin (C-Fc)
CU73-10ug 10ug
EUR 131
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Mouse Podoplanin (C-Fc)
CU73-1mg 1mg
EUR 1674
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Mouse Podoplanin (C-Fc)
CU73-500ug 500ug
EUR 1166
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Mouse Podoplanin (C-Fc)
CU73-50ug 50ug
EUR 273
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Mouse Podoplanin (PDPN) ELISA Kit
20-abx154564
  • EUR 7378.00
  • EUR 3933.00
  • EUR 911.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Shipped within 5-7 working days.

Mouse Podoplanin, Pdpn ELISA KIT
ELI-06723m 96 Tests
EUR 865

Mouse Podoplanin (PDPN) ELISA Kit
abx571749-96tests 96 tests
EUR 786
  • Shipped within 5-12 working days.

Mouse Podoplanin (PDPN) CLIA Kit
20-abx493858
  • EUR 7973.00
  • EUR 4246.00
  • EUR 981.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Please enquire.

Podoplanin (PDPN) Polyclonal Antibody (Mouse)
4-PAC719Mu01
  • EUR 251.00
  • EUR 2576.00
  • EUR 640.00
  • EUR 316.00
  • EUR 215.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PDPN (Gly23~Val138)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Podoplanin (PDPN)

Mouse Podoplanin (PDPN) ELISA Kit
SEC719Mu-10x96wellstestplate 10x96-wells test plate
EUR 4862.4
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Mouse Podoplanin (PDPN) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Podoplanin (PDPN) in tissue homogenates, cell lysates and other biological fluids.

Mouse Podoplanin (PDPN) ELISA Kit
SEC719Mu-1x48wellstestplate 1x48-wells test plate
EUR 488.08
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Mouse Podoplanin (PDPN) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Podoplanin (PDPN) in tissue homogenates, cell lysates and other biological fluids.

Mouse Podoplanin (PDPN) ELISA Kit
SEC719Mu-1x96wellstestplate 1x96-wells test plate
EUR 654.4
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Mouse Podoplanin (PDPN) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Podoplanin (PDPN) in tissue homogenates, cell lysates and other biological fluids.

Mouse Podoplanin (PDPN) ELISA Kit
SEC719Mu-5x96wellstestplate 5x96-wells test plate
EUR 2644.8
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Mouse Podoplanin (PDPN) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Podoplanin (PDPN) in tissue homogenates, cell lysates and other biological fluids.

Mouse Podoplanin (PDPN) ELISA Kit
4-SEC719Mu
  • EUR 4913.00
  • EUR 2595.00
  • EUR 655.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
  • Known also as Podoplanin elisa. Alternative names of the recognized antigen: GP40
  • GP36
  • Gp38
  • HT1A-1
  • OTS8
  • PA2.26
  • T1A
  • T1A-2
  • Aggrus
  • Glycoprotein 36
  • PA2.26 antigen
  • T1-alpha
  • Lung Type I Cell Membrane Associated Glycoprotein
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Podoplanin (PDPN) in samples from tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.

Mouse Podoplanin(PDPN)ELISA kit
QY-E21215 96T
EUR 361

Mouse Podoplanin (PDPN) ELISA Kit
RDR-PDPN-Mu-48Tests 48 Tests
EUR 557

Mouse Podoplanin (PDPN) ELISA Kit
RDR-PDPN-Mu-96Tests 96 Tests
EUR 774

Mouse Podoplanin (PDPN) ELISA Kit
RD-PDPN-Mu-48Tests 48 Tests
EUR 533

Mouse Podoplanin (PDPN) ELISA Kit
RD-PDPN-Mu-96Tests 96 Tests
EUR 740

Recombinant Human Podoplanin
7-05839 5µg Ask for price

Recombinant Human Podoplanin
7-05840 25µg Ask for price

Recombinant Human Podoplanin
7-05841 1mg Ask for price

Podoplanin Blocking Peptide
33R-2420 100 ug
EUR 180
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of PDPN antibody, catalog no. 70R-6816

Podoplanin Blocking Peptide
33R-9441 100 ug
EUR 180
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of PDPN antibody, catalog no. 70R-6817

Podoplanin Blocking Peptide
DF12456-BP 1mg
EUR 195

Podoplanin (PDPN) Antibody
20-abx008317
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul
  • Shipped within 5-10 working days.

Podoplanin (PDPN) Antibody
20-abx005408
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul
  • Shipped within 5-10 working days.

Podoplanin (PDPN) Antibody
20-abx178065
  • EUR 1233.00
  • EUR 592.00
  • 1 mg
  • 200 ug
  • Please enquire.

Podoplanin (PDPN) Antibody
20-abx178066
  • EUR 1302.00
  • EUR 620.00
  • 1 mg
  • 200 ug
  • Please enquire.

Podoplanin (PDPN) Antibody
20-abx178067
  • EUR 1414.00
  • EUR 662.00
  • 1 mg
  • 200 ug
  • Please enquire.

Podoplanin (PDPN) Antibody
20-abx211099
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul
  • Shipped within 5-10 working days.

Podoplanin (PDPN) Antibody
20-abx114559
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul
  • Shipped within 5-10 working days.

Podoplanin (PDPN) Antibody
20-abx123399
  • EUR 592.00
  • EUR 857.00
  • EUR 411.00
  • 100 ul
  • 200 ul
  • 50 ul
  • Shipped within 5-10 working days.

Podoplanin (PDPN) Antibody
20-abx129101
  • EUR 425.00
  • EUR 133.00
  • EUR 1205.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Podoplanin (PDPN) Antibody
20-abx131102
  • EUR 439.00
  • EUR 133.00
  • EUR 1233.00
  • EUR 592.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Podoplanin (PDPN) Antibody
20-abx137407
  • EUR 704.00
  • EUR 328.00
  • EUR 230.00
  • 100 ug
  • 20 ug
  • 5 ug
  • Shipped within 5-10 working days.

Podoplanin (PDPN) Antibody
20-abx174125
  • EUR 857.00
  • EUR 439.00
  • 1 mg
  • 200 ug
  • Please enquire.

Podoplanin (PDPN) Antibody
20-abx174126
  • EUR 913.00
  • EUR 467.00
  • 1 mg
  • 200 ug
  • Please enquire.

Podoplanin Blocking Peptide
20-abx063694
  • EUR 272.00
  • EUR 411.00
  • 1 mg
  • 5 mg
  • Shipped within 5-10 working days.

Podoplanin (PDPN) Protein
20-abx262003
  • EUR 4490.00
  • EUR 328.00
  • EUR 230.00
  • 1 mg
  • 25 ug
  • 5 ug
  • Shipped within 5-10 working days.

Podoplanin Conjugated Antibody
C49474 100ul
EUR 397

Podoplanin (PDPN) Antibody
20-abx339428
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul
  • Shipped within 5-10 working days.

Podoplanin (PDPN) Antibody
abx236598-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

Podoplanin (PDPN) Antibody
abx236599-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

Podoplanin (PDPN) Antibody
abx433110-200ul 200 ul
EUR 384
  • Shipped within 1-3 working days.

Recombinant Podoplanin (PDPN)
4-RPC719Hu01
  • EUR 413.60
  • EUR 214.00
  • EUR 1276.00
  • EUR 492.00
  • EUR 884.00
  • EUR 340.00
  • EUR 3040.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: Q86YL7
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 18.8kDa
  • Isoelectric Point: Inquire
Description: Recombinant Human Podoplanin expressed in: E.coli

Recombinant Podoplanin (PDPN)
4-RPC719Mu01
  • EUR 458.40
  • EUR 226.00
  • EUR 1444.00
  • EUR 548.00
  • EUR 996.00
  • EUR 370.00
  • EUR 3460.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: Q62011
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 42.2kDa
  • Isoelectric Point: Inquire
Description: Recombinant Mouse Podoplanin expressed in: E.coli

Syrian Hamster Anti-Mouse Podoplanin (gp38) Monoclonal antibody, clone 8.1.1
CABT-L4294-1mg 1 mg
EUR 897

Syrian Hamster Anti-Mouse Podoplanin (gp38) Monoclonal antibody, clone 8.1.1
CABT-L4294-5mg 5 mg
EUR 2405

ELISA kit for Mouse PDPN (Podoplanin)
E-EL-M2409 1 plate of 96 wells
EUR 534
  • Gentaur's PDPN ELISA kit utilizes the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Mouse PDPN. Standards or samples are added to the micro ELISA plate wells and combined with th
  • Show more
Description: A sandwich ELISA kit for quantitative measurement of Mouse PDPN (Podoplanin) in samples from Serum, Plasma, Cell supernatant

ELISA kit for Mouse PDPN (Podoplanin)
ELK7080 1 plate of 96 wells
EUR 432
  • The microtiter plate provided in this kit has been pre-coated with an antibody specific to Podoplanin (PDPN). Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody specific to Podoplanin (PDPN
  • Show more
Description: A sandwich ELISA kit for detection of Podoplanin from Mouse in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Podoplanin (PDPN) Polyclonal Antibody (Mouse), APC
4-PAC719Mu01-APC
  • EUR 351.00
  • EUR 3365.00
  • EUR 935.00
  • EUR 449.00
  • EUR 222.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PDPN (Gly23~Val138)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Podoplanin (PDPN). This antibody is labeled with APC.

Podoplanin (PDPN) Polyclonal Antibody (Mouse), Biotinylated
4-PAC719Mu01-Biotin
  • EUR 316.00
  • EUR 2526.00
  • EUR 744.00
  • EUR 387.00
  • EUR 221.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PDPN (Gly23~Val138)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Podoplanin (PDPN). This antibody is labeled with Biotin.

Podoplanin (PDPN) Polyclonal Antibody (Mouse), Cy3
4-PAC719Mu01-Cy3
  • EUR 427.00
  • EUR 4445.00
  • EUR 1205.00
  • EUR 557.00
  • EUR 254.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PDPN (Gly23~Val138)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Podoplanin (PDPN). This antibody is labeled with Cy3.

Podoplanin (PDPN) Polyclonal Antibody (Mouse), FITC
4-PAC719Mu01-FITC
  • EUR 301.00
  • EUR 2712.00
  • EUR 768.00
  • EUR 379.00
  • EUR 197.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PDPN (Gly23~Val138)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Podoplanin (PDPN). This antibody is labeled with FITC.

Podoplanin (PDPN) Polyclonal Antibody (Mouse), HRP
4-PAC719Mu01-HRP
  • EUR 321.00
  • EUR 2933.00
  • EUR 827.00
  • EUR 405.00
  • EUR 209.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PDPN (Gly23~Val138)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Podoplanin (PDPN). This antibody is labeled with HRP.

Podoplanin (PDPN) Polyclonal Antibody (Mouse), PE
4-PAC719Mu01-PE
  • EUR 301.00
  • EUR 2712.00
  • EUR 768.00
  • EUR 379.00
  • EUR 197.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PDPN (Gly23~Val138)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Podoplanin (PDPN). This antibody is labeled with PE.

Two artificial bacterial consortia (SC) composed of bacterial strains Sphingobium sp. (AM), Klebsiella aerogenes (B), Pseudomonas sp. (Bc-h and T), Burkholderia sp. (Bk) and Inquilinus limosus (Inq) remoted from a pure phenanthrene (PHN)-degrading consortium (CON) have been developed and evaluated as an various method to PHN biodegradation in bioremediation processes. A metabolic community displaying the potential function of strains was reconstructed by in silico examine of the six genomes and classification of dioxygenase enzymes utilizing RHObase and AromaDeg databases. The predicted roles have been additional confirmed by physiological, RT-qPCR and metaproteomic assays. SC-1 with AM as the sole PHN degrader was the most efficient. The ecological roles inferred in this examine might be utilized to optimize the design of bacterial consortia and sort out the biodegradation of complicated environmental pollution.

Comments are closed.